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Motif ID: RXR{A,B,G}.p2

Z-value: 2.339

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Top targets:

Promoter	Score	Refseq	Gene Symbol	Gene Name
chr17_+_44429748	6.387	NM_001160423 NM_006546	IGF2BP1	insulin-like growth factor 2 mRNA binding protein 1
chr19_+_18391423	3.316
chr19_+_18391211	3.115	NM_001009998 NM_032627	SSBP4	single stranded DNA binding protein 4
chr21_-_45532176	3.003	NM_015227 NM_133635	POFUT2	protein O-fucosyltransferase 2
chr22_+_18081968	2.676	NM_002688	SEPT5	septin 5
chr6_-_2916786	2.413		SERPINB6	serpin peptidase inhibitor, clade B (ovalbumin), member 6
chr18_+_75261231	2.400	NM_172387 NM_172389	NFATC1	nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 1
chr15_-_53822468	2.394	NM_173814	PRTG	protogenin
chr17_+_35751796	2.258	NM_001024809	RARA	retinoic acid receptor, alpha
chr12_+_50686990	2.246	NM_181711	GRASP	GRP1 (general receptor for phosphoinositides 1)-associated scaffold protein
chr20_+_48032918	2.207	NM_005985	SNAI1	snail homolog 1 (Drosophila)
chr8_-_93184629	2.018	NM_001198633 NM_175634	RUNX1T1	runt-related transcription factor 1; translocated to, 1 (cyclin D-related)
chr21_+_45649719	1.976
chr14_-_103058568	1.884		CKB	creatine kinase, brain
chr3_+_129690735	1.880
chr14_-_37795001	1.876		CLEC14A	C-type lectin domain family 14, member A
chr6_-_132314004	1.861	NM_001901	CTGF	connective tissue growth factor
chr11_+_14621972	1.824		PDE3B	phosphodiesterase 3B, cGMP-inhibited
chr6_-_2916280	1.802		SERPINB6	serpin peptidase inhibitor, clade B (ovalbumin), member 6
chr14_-_37795290	1.758	NM_175060	CLEC14A	C-type lectin domain family 14, member A
chr10_-_135036805	1.755	NM_004092	ECHS1	enoyl CoA hydratase, short chain, 1, mitochondrial
chr17_+_6867090	1.741	NM_181844	BCL6B	B-cell CLL/lymphoma 6, member B
chr1_-_47468029	1.698	NM_003189	TAL1	T-cell acute lymphocytic leukemia 1
chr22_+_18085891	1.615		SEPT5	septin 5
chr17_+_6867138	1.612		BCL6B	B-cell CLL/lymphoma 6, member B
chr11_-_124137260	1.564	NM_138961	ESAM	endothelial cell adhesion molecule
chr10_-_17536181	1.559	NM_001004470	ST8SIA6	ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 6
chr22_+_18085990	1.530		SEPT5-GP1BB SEPT5	SEPT5-GP1BB read-through transcript septin 5
chr4_+_134292630	1.491		PCDH10	protocadherin 10
chr2_+_27155197	1.479		EMILIN1	elastin microfibril interfacer 1
chr2_+_113709553	1.451		LOC654433	hypothetical LOC654433
chr20_-_23014828	1.451	NM_012072	CD93	CD93 molecule
chr16_-_87244896	1.447	NM_000101	CYBA	cytochrome b-245, alpha polypeptide
chr5_+_149845503	1.440		NDST1	N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 1
chr4_+_134293171	1.357		PCDH10	protocadherin 10
chr7_+_142788521	1.351		ZYX	zyxin
chr3_-_50335113	1.345	NM_003773 NM_033158	HYAL2	hyaluronoglucosaminidase 2
chr16_+_658158	1.344		RHOT2	ras homolog gene family, member T2
chr6_-_85529031	1.330		TBX18	T-box 18
chr11_-_86343737	1.315		FZD4	frizzled homolog 4 (Drosophila)
chr11_-_76059435	1.298	NM_001128922	LRRC32	leucine rich repeat containing 32
chr17_+_63799228	1.286		ARSG	arylsulfatase G
chr17_-_74433048	1.285	NM_003255	TIMP2	TIMP metallopeptidase inhibitor 2
chr21_+_45649429	1.276	NM_130445	COL18A1	collagen, type XVIII, alpha 1
chr5_-_172687798	1.259		STC2	stanniocalcin 2
chr16_+_66129481	1.258		FAM65A	family with sequence similarity 65, member A
chr17_+_78286687	1.250	NM_022158	FN3K	fructosamine 3 kinase
chr17_-_63798851	1.249	NM_001174166 NM_004694	SLC16A6	solute carrier family 16, member 6 (monocarboxylic acid transporter 7)
chr16_-_69277355	1.240	NM_138383	MTSS1L	metastasis suppressor 1-like
chr1_+_12149662	1.238		TNFRSF1B	tumor necrosis factor receptor superfamily, member 1B
chr16_+_658081	1.223	NM_138769	RHOT2	ras homolog gene family, member T2
chr1_-_152185764	1.209	NM_014856	DENND4B	DENN/MADD domain containing 4B
chr17_+_78630793	1.196	NM_001004431	METRNL	meteorin, glial cell differentiation regulator-like
chr2_+_241586927	1.179	NM_001080437	SNED1	sushi, nidogen and EGF-like domains 1
chr12_-_24946495	1.179	NM_001178094	BCAT1	branched chain amino-acid transaminase 1, cytosolic
chr3_-_16529996	1.172		RFTN1	raftlin, lipid raft linker 1
chr7_+_142788480	1.169	NM_001010972 NM_003461	ZYX	zyxin
chr19_+_17691302	1.158	NM_018174	MAP1S	microtubule-associated protein 1S
chr18_+_2896956	1.143		EMILIN2	elastin microfibril interfacer 2
chr5_-_172688024	1.137		STC2	stanniocalcin 2
chr7_+_2638108	1.129	NM_025250	TTYH3	tweety homolog 3 (Drosophila)
chr17_+_76988134	1.128	NM_001080519	BAHCC1	BAH domain and coiled-coil containing 1
chr9_+_35782405	1.120	NM_003995	NPR2	natriuretic peptide receptor B/guanylate cyclase B (atrionatriuretic peptide receptor B)
chr19_+_10574055	1.117	NM_001145056	SLC44A2	solute carrier family 44, member 2
chr11_+_65162114	1.113	NM_006747	SIPA1	signal-induced proliferation-associated 1
chr19_-_18409788	1.108	NM_001170939	ISYNA1	inositol-3-phosphate synthase 1
chr7_-_107430566	1.107	NM_002291	LAMB1	laminin, beta 1
chr10_+_94439658	1.100	NM_002729	HHEX	hematopoietically expressed homeobox
chr12_+_130979729	1.096	NM_001002019 NM_025215	PUS1	pseudouridylate synthase 1
chr19_+_59064471	1.089	NM_001020821 NM_001020818	MYADM	myeloid-associated differentiation marker
chr9_+_136673534	1.085		COL5A1	collagen, type V, alpha 1
chr10_-_30388439	1.084	NM_020848	KIAA1462	KIAA1462
chr19_+_18312365	1.080	NM_017712	FKBP8 PGPEP1	FK506 binding protein 8, 38kDa pyroglutamyl-peptidase I
chr19_+_59064795	1.077		MYADM	myeloid-associated differentiation marker
chr12_+_130979696	1.067	NM_001002020	PUS1	pseudouridylate synthase 1
chr11_+_43920385	1.061	NM_001145033	C11orf96	chromosome 11 open reading frame 96
chr1_-_1840564	1.060	NM_178545	TMEM52	transmembrane protein 52
chr4_-_10068055	1.052	NM_053042	ZNF518B	zinc finger protein 518B
chr2_-_74583850	1.052	NM_001009812	LBX2	ladybird homeobox 2
chr11_+_113436438	1.043	NM_001018011	ZBTB16	zinc finger and BTB domain containing 16
chr17_-_53420473	1.037		VEZF1	vascular endothelial zinc finger 1
chr7_+_142788569	1.033		ZYX	zyxin
chr19_-_40146792	1.020	NM_175872	ZNF792	zinc finger protein 792
chr7_+_142788566	1.018		ZYX	zyxin
chr12_+_52105131	1.011		AMHR2	anti-Mullerian hormone receptor, type II
chr16_-_71650034	1.010	NM_001164766	ZFHX3	zinc finger homeobox 3
chr17_+_44643067	1.005		ABI3	ABI family, member 3
chr2_+_27154938	1.004	NM_007046	EMILIN1	elastin microfibril interfacer 1
chr19_+_54723044	1.004		RCN3	reticulocalbin 3, EF-hand calcium binding domain
chr21_+_45532377	1.001		LOC642852	hypothetical LOC642852
chr4_+_184257337	0.996	NM_024949	WWC2	WW and C2 domain containing 2
chr11_-_86343859	0.993	NM_012193	FZD4	frizzled homolog 4 (Drosophila)
chr7_+_142788517	0.993		ZYX	zyxin
chr7_+_142788579	0.991		ZYX	zyxin
chr19_-_40146707	0.989		ZNF792	zinc finger protein 792
chr3_+_171558188	0.972		SKIL	SKI-like oncogene
chr17_-_74432800	0.968		TIMP2	TIMP metallopeptidase inhibitor 2
chr12_+_50587468	0.957	NM_000020	ACVRL1	activin A receptor type II-like 1
chr19_-_40938251	0.955		HSPB6	heat shock protein, alpha-crystallin-related, B6
chr5_-_131591380	0.953	NM_001017974 NM_001142598 NM_001142599	P4HA2	prolyl 4-hydroxylase, alpha polypeptide II
chr2_+_74583762	0.940		LOC151534	hypothetical LOC151534
chr7_+_2638156	0.939		TTYH3	tweety homolog 3 (Drosophila)
chr17_-_39796649	0.937	NM_198475	FAM171A2	family with sequence similarity 171, member A2
chr20_+_52525538	0.934	NM_018431	DOK5	docking protein 5
chr3_+_171558215	0.932		SKIL	SKI-like oncogene
chr12_-_113328271	0.925	NM_181486	TBX5	T-box 5
chr3_+_171558143	0.924	NM_001145098 NM_005414	SKIL	SKI-like oncogene
chr17_+_1905104	0.913	NM_006497	HIC1	hypermethylated in cancer 1
chr15_+_39008822	0.909	NM_019074	DLL4	delta-like 4 (Drosophila)
chr1_+_26671488	0.908	NM_005517	HMGN2	high-mobility group nucleosomal binding domain 2
chr1_-_210939820	0.907		BATF3	basic leucine zipper transcription factor, ATF-like 3
chr7_-_37454933	0.902	NM_014800	ELMO1	engulfment and cell motility 1
chr5_-_176857158	0.902		PDLIM7	PDZ and LIM domain 7 (enigma)
chr20_-_25514137	0.899	NM_025176	NINL	ninein-like
chr5_-_132141368	0.899	NM_001098813	SEPT8	septin 8
chr7_-_120285245	0.891		TSPAN12	tetraspanin 12
chrX_-_135677022	0.890		ARHGEF6	Rac/Cdc42 guanine nucleotide exchange factor (GEF) 6
chr13_-_20533703	0.886	NM_014572	LATS2	LATS, large tumor suppressor, homolog 2 (Drosophila)
chrX_+_153318662	0.876		GDI1	GDP dissociation inhibitor 1
chr6_+_69401660	0.875	NM_001704	BAI3	brain-specific angiogenesis inhibitor 3
chr2_-_127580975	0.875	NM_004305 NM_139343 NM_139344 NM_139345 NM_139346 NM_139347 NM_139348 NM_139349 NM_139350 NM_139351	BIN1	bridging integrator 1
chr7_-_124192265	0.871		GPR37	G protein-coupled receptor 37 (endothelin receptor type B-like)
chr9_-_16860719	0.871	NM_017637	BNC2	basonuclin 2
chr19_+_17691283	0.871		MAP1S	microtubule-associated protein 1S
chr11_+_67563093	0.861		TCIRG1	T-cell, immune regulator 1, ATPase, H+ transporting, lysosomal V0 subunit A3
chr16_+_88315452	0.859	NM_001113525	ZNF276	zinc finger protein 276
chr7_-_150283794	0.839	NM_172057	KCNH2	potassium voltage-gated channel, subfamily H (eag-related), member 2
chr19_-_55046718	0.839		LOC100506033	hypothetical LOC100506033
chr12_+_50104859	0.838	NM_001039960 NM_004858	SLC4A8	solute carrier family 4, sodium bicarbonate cotransporter, member 8
chr19_-_40938046	0.838		HSPB6	heat shock protein, alpha-crystallin-related, B6
chr2_-_192767494	0.837		TMEFF2	transmembrane protein with EGF-like and two follistatin-like domains 2
chr9_+_136673464	0.836	NM_000093	COL5A1	collagen, type V, alpha 1
chr11_-_63440891	0.834	NM_173587	RCOR2	REST corepressor 2
chr16_+_30815428	0.825	NM_001142544 NM_001330	CTF1	cardiotrophin 1
chr19_+_6323443	0.823	NM_032306	ALKBH7	alkB, alkylation repair homolog 7 (E. coli)
chr3_-_38666122	0.820	NM_000335 NM_001099404 NM_001099405 NM_198056 NM_001160160 NM_001160161	SCN5A	sodium channel, voltage-gated, type V, alpha subunit
chr10_+_80569464	0.820		ZMIZ1	zinc finger, MIZ-type containing 1
chr19_+_16860807	0.814	NM_003950	F2RL3	coagulation factor II (thrombin) receptor-like 3
chr17_-_53420595	0.813	NM_007146	VEZF1	vascular endothelial zinc finger 1
chr5_-_176857207	0.811	NM_005451 NM_203352 NM_213636	PDLIM7	PDZ and LIM domain 7 (enigma)
chr1_-_210939929	0.809	NM_018664	BATF3	basic leucine zipper transcription factor, ATF-like 3
chr10_+_97794139	0.807
chr17_-_74432671	0.805		TIMP2	TIMP metallopeptidase inhibitor 2
chr22_+_41279811	0.801	NM_014509	SERHL2	serine hydrolase-like 2
chr13_-_20533629	0.796		LATS2	LATS, large tumor suppressor, homolog 2 (Drosophila)
chr19_-_54350457	0.796	NM_002152	HRC	histidine rich calcium binding protein
chr21_+_46342440	0.795	NM_001849 NM_058174 NM_058175	COL6A2	collagen, type VI, alpha 2
chr7_+_128219307	0.793	NM_022742	CCDC136	coiled-coil domain containing 136
chr7_+_142788730	0.792		ZYX	zyxin
chr17_-_75808680	0.790	NM_000199	SGSH	N-sulfoglucosamine sulfohydrolase
chr12_+_105873669	0.789	NM_152261	C12orf23	chromosome 12 open reading frame 23
chr20_-_43972949	0.788		PLTP	phospholipid transfer protein
chr12_+_50104936	0.787		SLC4A8	solute carrier family 4, sodium bicarbonate cotransporter, member 8
chr12_+_130979994	0.786		PUS1	pseudouridylate synthase 1
chr8_+_69027166	0.786		PREX2	phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchange factor 2
chr17_+_71097147	0.780		MYO15B	myosin XVB pseudogene
chr7_+_78920846	0.780		LOC100505881	hypothetical LOC100505881
chr19_-_13074669	0.778		LYL1	lymphoblastic leukemia derived sequence 1
chr19_-_55046117	0.777		LOC100506033	hypothetical LOC100506033
chr17_-_6887965	0.777	NM_153357	SLC16A11	solute carrier family 16, member 11 (monocarboxylic acid transporter 11)
chr12_+_12829807	0.766	NM_030817	APOLD1	apolipoprotein L domain containing 1
chr11_+_117906965	0.763	NM_001144034 NM_001144035 NM_001144036 NM_001144037 NM_001144038 NM_032780	TMEM25	transmembrane protein 25
chr10_+_76256305	0.759	NM_012330	MYST4	MYST histone acetyltransferase (monocytic leukemia) 4
chr10_+_17310475	0.759		VIM	vimentin
chr8_+_16929116	0.757	NM_181723	EFHA2	EF-hand domain family, member A2
chr11_-_105398118	0.757	NM_032424	KIAA1826	KIAA1826
chr17_-_45562112	0.754	NM_174920	SAMD14	sterile alpha motif domain containing 14
chr9_-_16860664	0.750		BNC2	basonuclin 2
chr19_-_7244876	0.748	NM_000208 NM_001079817	INSR	insulin receptor
chr17_+_56831951	0.741	NM_005994	TBX2	T-box 2
chr16_-_1369613	0.740	NM_001193389 NM_023076	UNKL	unkempt homolog (Drosophila)-like
chr7_-_81910740	0.739		CACNA2D1	calcium channel, voltage-dependent, alpha 2/delta subunit 1
chr3_-_127558747	0.734	NM_014079	KLF15	Kruppel-like factor 15
chr19_-_13074973	0.732	NM_005583	LYL1	lymphoblastic leukemia derived sequence 1
chr8_+_69027277	0.731		PREX2	phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchange factor 2
chr17_+_16259573	0.731	NM_016113	TRPV2	transient receptor potential cation channel, subfamily V, member 2
chr11_+_117907083	0.729		TMEM25	transmembrane protein 25
chr19_+_55046229	0.729		PTOV1	prostate tumor overexpressed 1
chr9_-_130006309	0.727	NM_001131015 NM_012127	CIZ1	CDKN1A interacting zinc finger protein 1
chr19_+_55046088	0.724	NM_017432	PTOV1	prostate tumor overexpressed 1
chr7_-_81910956	0.719	NM_000722	CACNA2D1	calcium channel, voltage-dependent, alpha 2/delta subunit 1
chr19_-_12929008	0.716		GADD45GIP1	growth arrest and DNA-damage-inducible, gamma interacting protein 1
chr16_-_73857214	0.713	NM_001170720 NM_001170714 NM_001170718	BCAR1	breast cancer anti-estrogen resistance 1
chr17_-_1478293	0.713		SLC43A2	solute carrier family 43, member 2
chr20_+_32755778	0.712	NM_021202	TP53INP2	tumor protein p53 inducible nuclear protein 2
chr17_-_33179118	0.707	NM_000458 NM_001165923	HNF1B	HNF1 homeobox B
chr7_-_126679540	0.705	NM_001127323	GRM8	glutamate receptor, metabotropic 8
chr6_-_2916980	0.704		SERPINB6	serpin peptidase inhibitor, clade B (ovalbumin), member 6
chr5_-_132140786	0.704	NM_001098811 NM_001098812 NM_015146	SEPT8	septin 8
chr9_-_13269562	0.702		MPDZ	multiple PDZ domain protein
chr1_-_234295005	0.702		NID1	nidogen 1
chr10_-_17536351	0.701		ST8SIA6	ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 6
chr6_-_37061902	0.700		MTCH1	mitochondrial carrier homolog 1 (C. elegans)
chr11_-_124175493	0.692	NM_024631	C11orf61	chromosome 11 open reading frame 61
chr19_-_12929033	0.691	NM_052850	GADD45GIP1	growth arrest and DNA-damage-inducible, gamma interacting protein 1
chr7_+_94374862	0.690	NM_001166160 NM_017650	PPP1R9A	protein phosphatase 1, regulatory (inhibitor) subunit 9A
chr14_+_23937766	0.687	NM_025081	NYNRIN	NYN domain and retroviral integrase containing
chr20_+_62158882	0.685	NM_198723	TCEA2	transcription elongation factor A (SII), 2
chr22_-_17891777	0.684		CLDN5	claudin 5
chr17_-_16197433	0.678	NM_181716	CENPV	centromere protein V

Gene overrepresentation in process category:

enrichment	p-value	GO term	description
1.13	7.28e-05	GO:0065007	biological regulation
1.29	2.77e-04	GO:0048519	negative regulation of biological process
1.47	3.66e-04	GO:0006357	regulation of transcription from RNA polymerase II promoter
1.08	4.84e-04	GO:0009987	cellular process
1.29	6.11e-04	GO:0051252	regulation of RNA metabolic process
1.60	6.30e-04	GO:0010629	negative regulation of gene expression
1.13	7.03e-04	GO:0050789	regulation of biological process
1.13	7.82e-04	GO:0050794	regulation of cellular process
1.26	8.77e-04	GO:0010468	regulation of gene expression
1.27	1.64e-03	GO:2000112	regulation of cellular macromolecule biosynthetic process
1.20	2.72e-03	GO:0032502	developmental process
1.28	2.86e-03	GO:0048523	negative regulation of cellular process
1.60	3.00e-03	GO:0051253	negative regulation of RNA metabolic process
1.25	4.75e-03	GO:0010556	regulation of macromolecule biosynthetic process
1.24	4.86e-03	GO:0019219	regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.34	5.04e-03	GO:0009653	anatomical structure morphogenesis
1.54	6.05e-03	GO:2000113	negative regulation of cellular macromolecule biosynthetic process
1.21	6.10e-03	GO:0060255	regulation of macromolecule metabolic process
1.27	6.49e-03	GO:0006355	regulation of transcription, DNA-dependent
1.52	6.66e-03	GO:0010558	negative regulation of macromolecule biosynthetic process
1.58	6.70e-03	GO:0045892	negative regulation of transcription, DNA-dependent
1.50	1.12e-02	GO:0031327	negative regulation of cellular biosynthetic process
1.53	1.18e-02	GO:0045934	negative regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.23	1.31e-02	GO:0051171	regulation of nitrogen compound metabolic process
1.20	1.88e-02	GO:0048856	anatomical structure development
1.48	1.92e-02	GO:0009890	negative regulation of biosynthetic process
1.44	2.04e-02	GO:0051128	regulation of cellular component organization
1.22	2.12e-02	GO:0031326	regulation of cellular biosynthetic process
1.51	2.15e-02	GO:0051172	negative regulation of nitrogen compound metabolic process
1.19	2.51e-02	GO:0007275	multicellular organismal development
1.19	2.58e-02	GO:0016043	cellular component organization
1.22	2.68e-02	GO:0009889	regulation of biosynthetic process
2.13	2.98e-02	GO:0001503	ossification
1.40	3.22e-02	GO:0010605	negative regulation of macromolecule metabolic process
1.21	3.30e-02	GO:0048731	system development
2.96	3.69e-02	GO:0001649	osteoblast differentiation

Gene overrepresentation in compartment category:

enrichment	p-value	GO term	description
1.10	1.16e-04	GO:0043229	intracellular organelle
1.10	1.18e-04	GO:0043226	organelle
1.08	1.80e-04	GO:0044424	intracellular part
1.07	2.40e-04	GO:0005622	intracellular
1.10	1.07e-03	GO:0043231	intracellular membrane-bounded organelle
1.10	1.11e-03	GO:0043227	membrane-bounded organelle
1.70	7.87e-03	GO:0015629	actin cytoskeleton
1.12	2.53e-02	GO:0005634	nucleus

Gene overrepresentation in function category:

enrichment	p-value	GO term	description
1.49	9.22e-06	GO:0030528	transcription regulator activity
1.47	4.61e-05	GO:0001071	nucleic acid binding transcription factor activity
1.47	4.61e-05	GO:0003700	sequence-specific DNA binding transcription factor activity
1.28	1.29e-04	GO:0003677	DNA binding
1.54	2.89e-04	GO:0043565	sequence-specific DNA binding
1.12	1.06e-03	GO:0005515	protein binding
1.74	1.80e-03	GO:0016563	transcription activator activity
1.46	2.05e-02	GO:0005198	structural molecule activity